The normal levels in blood are in the range 2.5-4.5 mg/dl. The Phosphorus Cycle: Before the phosphorus can be used as nutrient for plants, we must wait for Mother Nature to perform its vital functions in order to take advantage of the raw materials that it offers.Phosphorus is an element classified as macro-nutrient since it directly participates - in large amounts - in the metabolism of all plants and especially in cannabis crops. Your kidneys are the primary regulators of phosphorus balance in your body but many medical conditions can affect your phosphorus level. Too much phosphorus can actually leach calcium from your bones, making them weak. It can also be quite useful for other symptoms that may be associated with either anxiety or … An excess of the mineral can cause diarrhea, as well as a hardening of organs and soft tissue. Even when Chronic Kidney Disease (CKD) patients limit foods that are high in phosphorus, most still find themselves with high phosphorus levels. High phosphorus usually causes itching of the skin. Phosphorus is an essential dietary nutrient that is concentrated in your bones and cells. The calcium and phosphate also can form crystals (calcify) in body tissue, including within the walls of the blood vessels. Please confirm that you are not located inside the Russian Federation. Although there are no specific signs directly attributable to the condition, symptoms will depend on the underlying cause of hyperphosphatemia. This can lead to algal blooms in water, which can kill fish and other plants. When you have too much potassium in your blood, it is called high potassium, or hyperkalemia. In addition, for every 1 mg/dL increase in phosphorus there is a 62% higher chance of death. Mar 1, 2017 #2 reeferfoxx 5000 Club Member View Badges. Not only does excessive phosphorous harm plants, it can also stay in your soil for years. Too much phosphate can be toxic. When you have kidney disease, your kidneys cannot remove extra potassium in the right way, and too much potassium can stay in your blood. But the truth is, we don’t know at this stage what the long-term impact of greywater use on gardens will be. Since your kidneys don't excrete phosphorus, the phosphorus you take into your body when eating is not excreted. As long as we get around 700mg of phosphorus on a daily basis, experts say that we should be fine. We do not control or have responsibility for the content of any third-party site. Its cosmic abundance is about one atom per 100 atoms of silicon, the standard. The high phosphorus gets into the skin and can also cause ulcers. Phosphorus can be found in cannabis anywhere from 0.1% to 0.5% of the overall weight. Why can't I eat high phosphorus-containing foods?Since your kidneys don't excrete phosphorus, the phosphorus you take into your body when eating is not excreted. Return to top. If high potassium has symptoms, you may experience muscle weakness. In fact, new research shows that the way you cook your foods can make a difference too. Additionally, dogs with bone diseases and calcium deficiency are susceptible to hyperphosphatemia. Too much phosphorus is typically caused by kidney disease, whereby the kidneys do not expel excess phosphorus. The Manual was first published as the Merck Manual in 1899 as a service to the community. Breathing in white phosphorus can cause you to cough or develop a condition known as phossy jaw that involves poor wound healing in the mouth and a breakdown of the jaw bone. First, as the calcium combines with the phosphorus, the calcium phosphate, which is essentially chalk, goes outside your blood system and hardens all the tissues it comes into contact with, such as your heart and your skin and muscles. I got my dogs blood work history from 6/2/18 for her insurance. Shallow-rooted annual and perennial plants frequently have iron and zinc deficiencies caused by excessive phosphorus. Without beneficial organisms, plants must put additional resources into root growth at the expense of other tissues and functions. Your kidneys are the primary regulators of phosphorus balance in your body but many medical conditions can affect your phosphorus level. If you put too much on your lawn you will burn the grass – which is just another way of saying you killed your grass. The roasted seeds of pumpkin and squash without salt provides 1174 mg of phosphorus per 100 gram. Hi. I have a 5 … Each ion has a … phosphorus. Controlling Phosphates in a Fish Aquarium . High-phosphorus fertiliser will kill Grevillea moonlight Very short Very narrow Fast Aus Yes No All year No Yes Evergreen Remove lower branches as it grows to form tree. The trusted provider of medical information since 1899, Hypernatremia (High Level of Sodium in the Blood), Hyponatremia (Low Level of Sodium in the Blood), Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH), Hyperkalemia (High Level of Potassium in the Blood), Hypokalemia (Low Level of Potassium in the Blood), Hypercalcemia (High Level of Calcium in the Blood), Hypocalcemia (Low Level of Calcium in the Blood), Hypermagnesemia (High Level of Magnesium in the Blood), Hypomagnesemia (Low Level of Magnesium in the Blood), Hyperphosphatemia (High Level of Phosphate in the Blood), Hypophosphatemia (Low Level of Phosphate in the Blood). Its cosmic abundance is about one atom per 100 atoms of silicon, the standard. Whether you need a pond high in productivity or prefer a pond that's clear, it's important to understand that phosphorus is the key to management in most scenarios. Plus, if your phosphorus is really high, we can't give you vitamin D you receive on dialysis (Zemplar) which you need to keep the PTH down and preserve your bones. Its high chemical reactivity assures that it does not occur in the free state (except in a … Hyperphosphatemia is rare except in people with severe kidney dysfunction. An excess of nutrients tends to speed up the growth of algae and diminish the availability of dissolved oxygen. Chronically high phosphorus levels in the blood can impact health and life expectancy. Zinc deficiencies show a bleaching of the tissue. But just choosing the right foods isn't the only dietary approach to managing your condition. Abnormally high or low levels may cause serious metabolic problems. You can benefit from the alkaline diet; this diet is also called as alkaline acid diet or alkaline ash diet. As the matter breaks down, nitrogen is made available to the plants. And if the fertilizer contains too much potassium and phosphorus, it creates excessive soil salts that trees may be unable to tolerate. Phosphorus is a very widely distributed element—12th most abundant in crustEarth’s, to which it contributes about 0.10 weight percent. I am curious to know how much phosphate can actually kill my tank? However, in people with severe kidney dysfunction, calcium combines with phosphate, which lowers calcium levels in the blood (a disorder called hypocalcemia). In these people, the kidneys do not excrete enough phosphate. But grass, just like every other plant, can’t grow without nitrates. Q: The phosphorous level in my mother is very high.What should be done to reduce it? Cuttlefish, a mollusk related to … However, getting too much phosphorus can be … People with kidney disease can work with a renal dietitian and their doctor to keep their phosphorus level in balance. So on warm summer nights during algal blooms, the dissolved-oxygen concentration sometimes drops too low for the fish, and a die-off can occur.This can occur as a result of purely natural conditions or because of human activity that results in adding nutrients, nitrogen and phosphorus, to water systems.Nutrients come from many sources: fertilizers, automobiles, sewage, manure, and others. Although we are not in your shoes, we know how difficult it is to lie under the dietary restrictions of dialysis. People with kidney disease can work with a renal dietitian and their doctor to keep their phosphorus level in balance. When there is an increase or decrease in the value about the stated numbers, the individual suffering from chronic kidney disease can seek assistance from a dietician who will perform a series of tests to find out the accurate value of the phosphorus content. Algae thrive when there is warm water, lots of sunlight, and a source of nitrogen and phosphorous. High phosphorus can lead to calciphylaxis. For more information on keeping track of phosphorus in the foods you eat, recipes low in phosphorus, and cooking demonstrations for low-phosphorus recipes, visit Kidney Kitchen. Nutrients come from many sources: fertilizers, automobiles, sewage, manure, and others. Lawn grasses, such as St. Augustine, are particularly sus- ceptible to iron and zinc defi-ciencies because grasses need high levels of iron and have shallow root systems. Dialysis removes some phosphorus, but not as much as your kidneys would remove. Attracts honey eaters. Most people with hyperphosphatemia do not have symptoms. Regular blood tests will show if the phosphorus level in their blood is too high or too low. Many types of seafood are good sources of phosphorus. As a rule of thumb we generally discourage using manures and compost around natives as it is difficult to attain how much nutrient will be released. © 2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA), © 2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, Athletes taking large doses of androgens to increase muscle bulk, Overuse of erectile dysfunction medications by men. It's a race of reproductive growth that is faster with more phosphates (up to a limit determined by sunlight and temperature) vs. killing by chlorine. To keep phosphorus at the correct level, you may need to take a phosphate binder (i.e. You are unable tot excrete the phosphorus that you take in with your food, which is food in protein-containing items, such as dairy products and meats. The amount of phosphorus found in these seeds can be as high as 1233 mg per 100 gram. This can lead to dangerously high levels of phosphorus in the blood. , MD, Brookwood Baptist Health and Saint Vincent’s Ascension Health, Birmingham, (See also Overview of Electrolytes and Overview of Phosphate's Role in the Body.). Should I be worried? Phosphate is one of the body's electrolytes, which are minerals that carry an electric charge when dissolved in body fluids such as blood, but the majority of phosphate in the body is uncharged. Phosphorus (P) is a big part of cannabis growth cycle and plants use phosphorus the most at the seedling and flowering stages of its growth. This site complies with the HONcode standard for trustworthy health information: verify here. Last full review/revision Apr 2020| Content last modified Apr 2020. Phosphorus is an essential element for plant life, but when there is too much of it in water, it can speed up eutrophication (a reduction in dissolved oxygen in water bodies caused by an increase of mineral and organic nutrients) of rivers and lakes. If you would like to learn more about how the condition affects cats, please visit this page in the PetMD health library. Less energy is then available for growing, flowering and fruiting. Symptoms and Types. In hyperphosphatemia, the level of phosphate in blood is too high. East Clinic 4600 American Parkway Madison, WI 53718-8337 (608) 270-5600, Fitchburg Clinic 3034 Fish Hatchery Road Fitchburg, WI 53713 (608) 270-5600. Once your phosphorus level goes below 5.5 mg/dL on a regular basis, your dietitian may be able to help you safely include an occasional high-phosphorus food into your kidney diet . I am … Second, you take "binders," which are pills which bind up the phosphorus in your food before your stomach can absorb it into your system. If you don’t get enough phosphorus, symptoms of a deficiency can include anxiety, decreased appetite, irritability, breathing difficulty, laziness, and changes to mood. The desired level of phosphorus is 3.5 – 5.5. Phosphorus buildup is caused by excessive use of in-organic fertilizer or the use of composts and manures high in phosphorus. I checked my phosphate and it was at .25. When you need additional phosphorus, use an organic source such as bone meal, soy meal, manure, or bat guano. Phosphorus is an essential mineral your body needs for maintaining healthy bones, cell membranes and energy production, but overconsuming phosphorus can cause high serum levels of phosphate, also known as hyperphosphatemia, especially in people with kidney problems. Having too much potassium in your blood can be dangerous. H Severe arteriosclerosis (hardening of the arteries) can result, leading to strokes, heart attacks, and poor circulation. If you have a kidney condition like chronic kidney disease, you may have high levels of phosphorus. What is high phosphorus (hyperphosphatemia)? Phosphorus is commonly used for: Anxiety and Fear: Phosphorus works quite well in curing anxiety and fear in and of itself. The legacy of this great resource continues as the MSD Manual outside of North America. By exfoliating layered black phosphorus using the same method applied to obtain graphene from graphite, 2D black phosphorus … Because phosphorus is not as tightly regulated by the body as calcium, phosphate levels in your blood can rise slightly with a high phosphorus diet, especially after meals. High phosphorous levels in your soil are usually the culprit of over-fertilizing or adding too much manure. Fairclough says some people are more prone to the affects of a high salt diet. This element is used in such processes as photosynthesis and energy transfer. While Dialysis Treatments remove some phosphorus from the body, it cannot replace the kidneys and patients are at constant risk of high phosphorus (Hyperphosphatemia). Phosphorus exists in three forms in nature: (i) White phosphorus used as firecrackers, (ii) red phosphorus used in matches, and (iii) black phosphorus obtained by phase transformation of white phosphorus or red phosphorous at high temperature and pressure. “Eating too much cheese with its high saturated fat and salt content can contribute to high blood pressure,” he adds. Second only to calcium, phosphorous is the most plentiful mineral in your body, and it is necessary for such processes as the production and storage of energy. The calcium and phosphate also can form crystals (calcify) in body tissue, including within the walls of the blood vessels. It is a key macronutrient that cannot be ignored if you want to grow strong and hearty plants and vegetables. However, as long as phosphate levels are below 100 ppb and you're maintaining proper pH, water level, chlorine level, and total alkalinity, algae growth shouldn't be a problem. Second, as the calcium leaves the blood system with the phosphorus, the lower calcium amount in your blood causes a hormone called PTH to be released, which take the calcium out of your bones to keep the calcium normal in the bloodstream. A:Phosphorus is an important element, which is required for strengthening bones and for the normal functioning of cells & energy metabolism.Most of the phosphorous in the body (~90%) is present in the bone. As you now know, phosphorus enters your pond on the sly through fish and fish food, plants and fertilizers, runoff, rain, and even geese. You can actually kill a tree if you apply too much fertilizer. What happens to my body if my phosphorus level is higher than 5.5 mg/dl?When the phosphorus level goes up, it combines with the calcium in your blood. ... (Largest Dialysis Organization in the U.S.) calls the mineral a "Silent Disease," that "can kill!" If your body is unable to properly filter out and discard excess phosphorus, this could lead to a buildup. Share on Pinterest Kidney disease and diabetes are common causes of hyperphosphatemia. So what does high phosphorus mean for my body?You get hardening of the arteries all over your body, you may get very serious skin ulcers, and your bones get soft. In healthy individuals, the kidneys excrete excess phosphorus with the help of various endocrine hormones, so high phosphorus levels are not a concern. Sevelamer and lanthanum are often used for people undergoing dialysis because calcium compounds can make calcium-phosphate crystals more likely to form in tissues. Not only does excessive phosphorous harm plants, it can also stay in your soil for years. LisaAnn . The safe level of phosphorus content of the body is 2.5 to 4.5 mg/dL. Phosphorus is another first aid kit must have. Phosphate levels are normally higher in children than in adults because their bones are actively growing. Foods that are high in phosphate, such as milk, egg yolks, chocolate, and soft drinks, should be avoided. AndysReef said: Some of you may know that recently I lost a pair of clownfish a few days ago. High phosphorus levels can also cause bone pain, muscle fatigue, and even heart problems. Chicken manure is high in Phosphorus and should be avoided on Phosphorus sensitive plants. Drugs that bind with phosphate, such as sevelamer, lanthanum, and calcium compounds, should be taken with meals as prescribed by a doctor. You describe using lots of soil coverings which may contribute to higher amounts of organic matter in the soil. Thus, the phosphorus level rises in your blood, with multiple bad effects on your body. Mushroom compost should be avoided as it raises soil pH and can kill soil bacteria. Antacids such as Tums, are used as effective binders to prevent phosphorus absorption by combining with the phosphorus in CKD patients' intestinal tract. Most importantly, high phosphorus can kill Chronic Kidney Disease and Dialysis patients, suggested Fresenius Medical Care Inc. The link you have selected will take you to a third-party website. Second only to calcium, phosphorous is the most plentiful mineral in your body, and it is necessary for such processes as the production and storage of energy. The diagnosis of hyperphosphatemia is based on blood tests indicating that the phosphate level is high. The level of phosphorus in your blood will help determine if you are eating too many high phosphorus foods and if you need to be on medication to help control the phosphorus level in your blood. Its high chemical reactivity assures that it does not occur in the free state (except in a … Identify and describe three human behaviors that impact the phosphorus cycle Humans can both raise livestock and use fertilizers which both can due to their waste, which is high in phosphorus which can both make its way to the soil. The Manual was first published as the Merck Manual in 1899 as a service to the community. "The rate of chlorine kill is the same [with high phosphates], but the rate of growth can be slower with low phosphates. You Can have Too Much Compost. The vet never mentioned anything was wrong with her on th chart it says "insignificant". So why call phosphorus a killer?Because hardening of the arteries, either to your heart or the rest of your body, is the number one killer of people on dialysis, or even with people who aren't yet on dialysis but have kidney disease. These drugs make phosphate harder to absorb, and more phosphate is excreted. This can lead to itching, brittle bones, painful sores which may not heal, Calcification (stiff or less flexible veins and arteries), heart attack, stroke, hospitalizations, and even death. Iron deficiencies are characterized by yellowing between the leaf veins. Most of what is known about the health effects of breathing this compound is from studies of workers. If you control the phosphorus, the hardening of the arteries slows down or stops. Seafood. Two bad things happen from that combination. As mentioned before, high phosphates in a pool can promote algae growth, leading to a green and cloudy pool. Severe arteriosclerosis (hardening of the arteries) can result, leading to strokes, heart attacks, and poor circulation. High potassium and phosphorus levels doesn't mean you have low nitrogen. Nitrates are similar. … What is the goal for my phosphorus level?In patients on dialysis, we want to keep your phosphorus level below 5.5 mg/dl. Occasionally, the only symptom of high blood potassium is a sudden heart arrhythmia that can result in heart attack. The symptoms of high potassium are usually none. Low phosphate levels in children can inhibit bone growth and high levels may be an indication of a condition that disrupts the body's balance of minerals. Joined Sep 8, 2015 Messages 6,515 Reaction score 6,464. While rock phosphate is considered an organic source of phosphorus, the radioactive byproducts formed during production can be detrimental to the environment. Why can't I eat high phosphorus-containing foods? Without mycorrhizal fungi, plants need to expend more energy making larger root systems. Measurement of phosphate levels in the blood. That is why you should take your binders when you start to eat, not after you eat. R2R Supporter. Also, high levels of phosphorus, either from chemical fertilizers or natural sources such as bone meal or rock phosphate, can inhibit growth of beneficial soil organisms called mycorrhizal fungi. The amount of phosphorus in these are ranked according to the content of phosphorus in 100 gram. Dialysis, often used to treat kidney dysfunction, is not very effective at removing phosphate and thus does not reduce the risk of hyperphosphatemia. Applying high levels of quick- release nitrogen can burn the roots when applied to the soil and can burn the foliage when applied as a foliar spray or drench. Thus, the phosphorus level rises in your blood, with multiple bad effects on your body. Dialysis removes some phosphorus, but not as much as your kidneys would remove. Over time this can create bonelike crystals. Hyperphosphatemia is when you have too much phosphate in your blood. Causes calciphylaxis. Phosphorus is a very widely distributed element—12th most abundant in crustEarth’s, to which it contributes about 0.10 weight percent. This can call for additional nitrogen because nitrogen is bound up in the organic matter. I am not noticing the phosphorus levels say 6.5 high from a range of 2.5-6.0. It can occur at any age but is more common in puppies or old dogs with kidney problems. Damage to the blood vessels of the mouth has been observed in rats breathing air containing white phosphorus. How do I keep my phosphorus below 5.5 mg/dl in my blood?First, the dietitians counsel you on a low phosphorus diet. Phosphorus Fertilizers – applying a fertilizer with a high phosphorous content in the NPK ratio (example: 10-20-10, ... you can see it’s fairly simple to ensure you have a balanced amount of phosphorous in soil. Phosphorus is an essential dietary nutrient that is concentrated in your bones and cells. Regular blood tests will show if the phosphorus level in their blood is too high or too low. What is a normal phosphorus level in the body?If your kidneys were working, your kidneys would excrete the phosphorus and keep your blood levels at 2.5-4.5 mg/dl. Phosphorus is an essential component in soil but if you put to much it can kill the plant in the soil. High potassium can even cause a heart attack or death! High-phosphorus fertiliser will kill Gungurru Eucalyptus caesia ‘caesia’ Short Narrow Medium WA Yes No Spring No No Evergreen Daintier, more 'tree-like' version of the Silver Princess. Merck and Co., Inc., Kenilworth, NJ, USA (known as MSD outside of the US and Canada) is a global healthcare leader working to help the world be well. High phosphorous levels in your soil are usually the culprit of over-fertilizing or adding too much manure. We want you to eat good amount of protein, but limit phosphorus intake. Virilization is the development of exaggerated masculine characteristics, usually in women, often as a result of the adrenal glands overproducing androgens (male hormones). In people with kidney dysfunction, hyperphosphatemia is treated by reducing consumption of phosphate and reducing absorption of phosphate from the digestive tract. Many annual bedding plants and newly planted perennial shrubs also can show symptoms. When you apply soluble phosphorus fertilizers, such as super phosphate, to the soil, chemical reactions cause this readily available phosphorus to revert to … Detergent can also affect the cycle which contains tripolyphosphate. The reports also show that the cancer cells produce an acidic environment due to a high-metabolic-rate. "The rate of chlorine kill is the same [with high phosphates], but the rate of growth can be slower with low phosphates. Phosphorus can be found in a wide variety of foods, from dairy to whole grains. High soil phospho-rus levels also can threaten streams, rivers, lakes and oceans. Crystals can also form in the skin, where they cause severe itching. Here is a list of 17 foods high in phosphorus you should eat regularly to avoid phosphorus deficiency. This can occur as a result of purely natural conditions or because of human activity that results in adding nutrients, nitrogen and phosphorus, to water systems. Which of the following is a cause of virilization that does not involve a tumor or cancer? The foods you eat have a major impact on your body's ability, combined with dialysis and medications, to control sodium, potassium, phosphorous and protein. High phosphorus levels are also toxic to mycorrhizal fungi which are very important to landscape plants. High phosphorus can cause the formation and deposit of a calcium and phosphorus structure in your veins and organs. This is rare, however, and it is more common that high phosphorus levels lead to cardiovascular disease or osteoporosis. It causes skin to melt away from the bone and can break down a victim's jawbone, but white phosphorus - known in Vietnam as Willie Pete - is still used by sections of the world's military. The normal amount of phosphorus in the blood (also called serum phosphorus) is between 2.5 – 4.5 mg/dL. Wave action and oceanic water currents return this inorganic phosphorus to the surface, where it can again be utilized by algae and other autotrophs. Both iron and zinc deficiencies occur in the youngest tissues and can occur at the same time, which … They provide phosphorus and water, as well as other nutrients to the plant. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. If you find that you have high phosphorus levels, try following some of the above tips to bring it under control. Every ion in fertilizer is both a food source for plants at low levels and a toxin at high levels. Low calcium can cause muscle cramps and spasms but also causes an increase in parathyroid hormone levels, resulting in bone weakness and other problems. Less commonly, hyperphosphatemia develops in people with the following: A low level of parathyroid hormone (hypoparathyroidism), Lack of response to a normal level of parathyroid hormone (pseudohypoparathyroidism), Destruction of muscle tissue (rhabdomyolysis), Large amounts of phosphate taken by mouth or given in an enema. Any sort of bleeding can be easily cured by turning to phosphorus as a homeopathic remedy. High soil phospho-rus levels also can threaten streams, rivers, lakes and oceans. Low phosphate levels in children can inhibit bone growth and high levels may be an indication of a condition that disrupts the body's balance of minerals. High levels of phosphorus and calcium in the blood can also cause itchy skin and red eyes. Abnormally high or low levels may cause serious metabolic problems. These seeds are consumed in 5 ways, they are whole seeds, roasted with salt or without salt. Soft drinks and pre-packaged food items are high in phosphorus content, which some nutritionists believe contributes to over-consumption of phosphorus. Learn more about our commitment to Global Medical Knowledge. High phosphorus can be particularly dangerous for the heart. Hyperphosphatemia can affect both dogs and cats. Risk of death increases at levels of phosphorus above 5.5 mg/dL. If you have questions about controlling your phosphorus, please ask your dietitian, nurse or physician. R2R Excellence Award. It helps by getting to the root cause of the problem and allowing the body to naturally heal whatever is leading to the bleeding gums, chronic bloody nose, heavy menstrual flow, or even bleeding from the stomach lining. Calciphylaxis is a condition that consists of painful sores on the skin that can … However, getting too much phosphorus can be … Hyperphosphatemia is an electrolyte disturbance in which abnormally elevated levels of phosphate are present in the dog's blood. Reef Squad Emeritus . Thanks . Hence, managing phosphorus is crucial to a Dialysis patient's health outco. The legacy of this great resource continues as the MSD Manual outside of North America. If you take … Causes. Recommended Reading: Over Forty Popular Beverages Outside Of Cola Contain Dangerous Phosphorus Levels For CKD Patients. While phosphorus levels great than 5.5 are a serious problem. As we have learnt, the use of greywater with a high content of laundry detergent can be quite harmful to plants, causing phosphorus toxicity and sodium issues. It's a race of reproductive growth that is faster with more phosphates (up to a limit determined by sunlight and temperature) vs. killing by chlorine.” This explains why chlorine demand tends to be higher with high phosphate levels in a swimming pool. Also, acid loving plants grown in neutral to alkaline soils display symptoms of deficiencies. A build up of phosphorus can be dangerous to your health.
2020 can high phosphorus kill you